SCHEMBL11545205

SCHEMBL11545205

C=Cc1ccccc1COC(=O)CCC(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.48
MAPT P10636 3/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
HPGD P15428 1/20 0.48
NR4A2 P43354 1/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
USP2 O75604 1/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
GAA P10253 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
CTNNB1 P35222 2/20 0.40
WNT3A P56704 2/20 0.40
PPARG P37231 1/20 0.38
HDAC3 O15379 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9472073 0.84 CYP4F2 (0.40) L3MBTL1KMT2AMEN1HPGDALDH1A1
SCHEMBL11414480 0.81 ALDH1A1 (0.35) L3MBTL1MAPTKMT2AMEN1ALDH1A1
SCHEMBL5143591 0.81 PPARG (0.56) L3MBTL1MAPTKMT2AHPGDALDH1A1
SCHEMBL9615715 0.78 ALDH1A1 (0.40) L3MBTL1MAPTKMT2AMEN1HPGD
SCHEMBL10775904 0.78 ALDH1A1 (0.36) L3MBTL1KMT2AMEN1ALDH1A1POLB
SCHEMBL10614676 0.77 TSHR (0.50) L3MBTL1MAPTKMT2AMEN1LMNA
SCHEMBL20224994 0.76 L3MBTL1 (0.59) L3MBTL1MAPTKMT2AMEN1HPGD
SCHEMBL2029842 0.74 THRB (0.46) HPGDALDH1A1LMNAMAPK1PPARG
SCHEMBL61037 0.74 ALDH1A1 (0.50) L3MBTL1MAPTKMT2AALDH1A1LMNA
SCHEMBL8164190 0.74 L3MBTL1 (0.65) L3MBTL1MAPTKMT2AMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4148987-A USED FOR DISPOSABLE PRODUCTS AND AS PRESSURE SENSITIVE ADHESIVES ROHM AND HAAS COMPANY (US) 1979-04-10 US disclosed