Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.54 |
| ▸ | IGF1R | P08069 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545449 | 0.89 | TRPV1 (0.52) | TRPV1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL11541220 | 0.85 | USP2 (0.53) | TRPV1USP2CYP3A4IGF1RALDH1A1 | |
| SCHEMBL11546873 | 0.84 | MAPT (0.59) | TRPV1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL11819414 | 0.84 | MAPT (0.52) | IGF1RALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11730578 | 0.80 | ADRB2 (0.51) | IGF1RMAPTACP1 | |
| SCHEMBL11731049 | 0.80 | TLR7 (0.49) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL11545275 | 0.80 | PRKAB2 (0.59) | USP2CYP3A4PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL11727561 | 0.79 | SIGMAR1 (0.58) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL11730686 | 0.77 | MAPKAPK2 (0.52) | ALDH1A1TSHRMAPTABL1 | |
| SCHEMBL11545237 | 0.76 | TRPV1 (0.52) | TRPV1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |