Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552737 | 0.86 | GSK3B (0.42) | HPGDKDM4ERAB9AGSK3BMAPT | |
| SCHEMBL11547093 | 0.82 | HPGD (0.48) | HPGDALOX15HTTLMNAKDM4E | |
| SCHEMBL11546525 | 0.81 | NLRP3 (0.49) | HPGDHTTKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL11547384 | 0.80 | GSK3B (0.37) | HPGDLMNAKDM4ERAB9AGSK3B | |
| SCHEMBL11546203 | 0.79 | HPGD (0.44) | HPGDLMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL11549836 | 0.78 | HPGD (0.39) | HPGDLMNAKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL11546286 | 0.76 | GSK3B (0.41) | HPGDSMN1; SMN2NPC1RAB9AGSK3B | |
| SCHEMBL11545577 | 0.75 | GSK3B (0.43) | KDM4ENPC1RAB9AGSK3BMAPT | |
| SCHEMBL11553122 | 0.75 | GSK3B (0.46) | HPGDKDM4ERAB9AGSK3BMEN1 | |
| SCHEMBL17488563 | 0.75 | NPC1 (0.58) | HPGDALOX15HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |