Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545125 | 0.84 | GSK3B (0.39) | GSK3BMEN1KMT2ATSHRMAPT | |
| SCHEMBL11553122 | 0.83 | GSK3B (0.46) | GSK3BALDH1A1PTPN1RAB9AMEN1 | |
| SCHEMBL11552737 | 0.82 | GSK3B (0.42) | GSK3BALDH1A1PTPN1RAB9AMEN1 | |
| SCHEMBL11545577 | 0.80 | GSK3B (0.43) | GSK3BALDH1A1PTPN1RAB9AMEN1 | |
| SCHEMBL11544341 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL11547089 | 0.79 | KMT2A (0.51) | GSK3BPTPN1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL11546525 | 0.77 | NLRP3 (0.49) | GSK3BALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11428878 | 0.77 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL11545679 | 0.77 | GSK3B (0.43) | GSK3BALDH1A1PTPN1RAB9AMEN1 | |
| SCHEMBL11547384 | 0.76 | GSK3B (0.37) | GSK3BALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |