Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910718 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11549538 | 0.88 | KDM4E (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11364474 | 0.85 | MAOB (0.55) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11548704 | 0.84 | NPC1 (0.57) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11364300 | 0.81 | TBK1 (0.47) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11369839 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11356167 | 0.80 | TBK1 (0.52) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11546384 | 0.77 | TBK1 (0.50) | — | |
| SCHEMBL11360715 | 0.77 | RAB9A (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11356293 | 0.76 | MAOB (0.54) | KDM4EALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |