Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901859 | 0.88 | TBK1 (0.58) | TBK1MEN1KMT2ATTRMAOA | |
| SCHEMBL11544400 | 0.85 | MEN1 (0.68) | TBK1MEN1KMT2ATTRMAOA | |
| SCHEMBL11548704 | 0.83 | NPC1 (0.57) | TBK1MEN1KMT2ATTRMAOB | |
| SCHEMBL11108273 | 0.81 | RAB9A (0.60) | KMT2AMAOBKDM4EALDH1A1GLA | |
| SCHEMBL11099411 | 0.81 | KMT2A (0.50) | TBK1MEN1KMT2ATTRMAOA | |
| SCHEMBL11550388 | 0.80 | KMT2A (0.49) | TBK1MEN1KMT2ATTRMAOA | |
| SCHEMBL11545315 | 0.80 | KDM4E (0.56) | MEN1KMT2AMAOAMAOBKDM4E | |
| SCHEMBL11364300 | 0.80 | TBK1 (0.47) | TBK1MEN1KMT2ATTRKDM4E | |
| SCHEMBL11099409 | 0.79 | KMT2A (0.48) | TBK1MEN1KMT2ATTRMAOA | |
| SCHEMBL11546384 | 0.76 | TBK1 (0.50) | TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | disclosed |