Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.50 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EIF4A1 | P60842 | 9/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906858 | 0.90 | TBK1 (0.59) | TBK1IKBKE | |
| SCHEMBL11364300 | 0.89 | TBK1 (0.47) | TBK1IKBKE | |
| SCHEMBL11358711 | 0.88 | TBK1 (0.49) | TBK1IKBKE | |
| SCHEMBL11548704 | 0.80 | NPC1 (0.57) | TBK1IKBKE | |
| SCHEMBL2907432 | 0.79 | TBK1 (0.56) | TBK1IKBKE | |
| SCHEMBL11357263 | 0.79 | TBK1 (0.60) | TBK1IKBKE | |
| SCHEMBL19196860 | 0.77 | TBK1 (0.80) | TBK1IKBKE | |
| SCHEMBL11545315 | 0.77 | KDM4E (0.56) | — | |
| SCHEMBL11374157 | 0.77 | TBK1 (0.44) | TBK1IKBKE | |
| SCHEMBL11362855 | 0.77 | RAB9A (0.51) | TBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |