Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 11/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540658 | 0.93 | SOAT1 (0.44) | SOAT1G6PDCYP2C9CYP2C19 | |
| SCHEMBL11542520 | 0.93 | SOAT1 (0.44) | SOAT1G6PDCYP2C9CYP2C19 | |
| SCHEMBL11542462 | 0.89 | SOAT1 (0.39) | SOAT1S100A4ALDH1A1 | |
| SCHEMBL11883307 | 0.84 | G6PD (0.43) | SOAT1S100A4G6PDP4HBCYP2C9 | |
| SCHEMBL11543271 | 0.77 | DGKA (0.47) | — | |
| SCHEMBL11543200 | 0.77 | S100A4 (0.39) | S100A4HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL11545537 | 0.76 | — | — | |
| SCHEMBL11545321 | 0.76 | TSHR (0.40) | ALDH1A1LMNA | |
| SCHEMBL6653246 | 0.74 | GBA1 (0.38) | G6PDHPGDALDH1A1LMNA | |
| SCHEMBL11545536 | 0.73 | PTGER4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180672-A | 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom | TEIJIN LIMITED (JP) | 1979-12-25 | — | — | US | disclosed |