Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545483 | 0.99 | SLC6A2 (0.33) | SLC6A4SLC6A2SLC6A3CHRM1ADRA1A | |
| SCHEMBL11545389 | 0.77 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3OPRM1HTR2A | |
| SCHEMBL11544443 | 0.76 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3CHRM1ADRA1A | |
| SCHEMBL11543869 | 0.76 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3CHRM1ADRA1A | |
| SCHEMBL11545456 | 0.74 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3CHRM1ADRA1A | |
| SCHEMBL11290087 | 0.73 | SLC6A2 (0.36) | SLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL11544440 | 0.69 | SLC6A3 (0.38) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL11544762 | 0.68 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3LMNAHTR2A | |
| SCHEMBL11552516 | 0.68 | PGR (0.35) | TSHRHSD17B10 | |
| SCHEMBL11544758 | 0.68 | SLC6A3 (0.42) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |