Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.42 |
| ▸ | TYMS | P04818 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12120523 | 0.88 | TXNRD1 (0.47) | CYP19A1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL10622390 | 0.79 | RELA (0.52) | CYP19A1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL11072978 | 0.78 | MERTK (0.55) | CYP19A1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL11545271 | 0.78 | MAPT (0.49) | CYP19A1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL4728549 | 0.77 | RELA (0.43) | CYP19A1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL1378967 | 0.75 | HSP90AA1 (0.62) | ALDH1A1HTTMAPTKMT2ARAB9A | |
| SCHEMBL11547830 | 0.75 | TXNRD1 (0.46) | CYP19A1HTTMAPTMAPK1S1PR4 | |
| SCHEMBL11544441 | 0.75 | KMT2A (0.51) | CYP19A1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL18956900 | 0.75 | MEN1 (0.48) | XDHALDH1A1HTTMAPTKMT2A | |
| SCHEMBL30072440 | 0.75 | MEN1 (0.48) | XDHALDH1A1HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |