Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12120523 | 0.80 | TXNRD1 (0.47) | KMT2AMAPTMEN1NPSR1CYP19A1 | |
| SCHEMBL10622390 | 0.80 | RELA (0.52) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL11072978 | 0.79 | MERTK (0.55) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL11545271 | 0.79 | MAPT (0.49) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL4728549 | 0.78 | RELA (0.43) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL20838499 | 0.76 | MEN1 (0.50) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL11545397 | 0.75 | XDH (0.45) | KMT2AMAPTSMN1; SMN2NPSR1CYP19A1 | |
| SCHEMBL1378967 | 0.73 | HSP90AA1 (0.62) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL11548951 | 0.73 | ADORA3 (0.44) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11543518 | 0.71 | MAPT (0.38) | KMT2AMAPTMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |