Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072978 | 0.85 | MERTK (0.55) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| SCHEMBL10622390 | 0.84 | RELA (0.52) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| SCHEMBL12120523 | 0.84 | TXNRD1 (0.47) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| SCHEMBL4728549 | 0.81 | RELA (0.43) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| SCHEMBL11544441 | 0.79 | KMT2A (0.51) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| SCHEMBL11545397 | 0.78 | XDH (0.45) | MAPTKMT2AMAPK1NPSR1ALDH1A1 | |
| SCHEMBL1378967 | 0.77 | HSP90AA1 (0.62) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| SCHEMBL11548951 | 0.76 | ADORA3 (0.44) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| SCHEMBL4728487 | 0.76 | MAPT (0.38) | MAPTKMT2AMAPK1MEN1NPSR1 | |
| Hydrochloric Acid SCHEMBL11543518 | 0.74 | MAPT (0.38) | MAPTKMT2AMAPK1MEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |