Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545284 | 0.85 | L3MBTL1 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL14879738 | 0.85 | NPC1 (0.76) | NPC1GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL3365303 | 0.85 | NPC1 (0.76) | NPC1GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL25934640 | 0.83 | NPC1 (0.79) | NPC1GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL11547174 | 0.83 | ALDH1A1 (0.53) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL20034969 | 0.79 | MEN1 (0.71) | NPC1GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL9062091 | 0.79 | NPC1 (0.81) | NPC1GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL11546455 | 0.77 | NPC1 (0.63) | NPC1GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL11546458 | 0.77 | NPC1 (0.63) | NPC1GNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL25123500 | 0.74 | GNAI3 (0.65) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144256-A | FATTY AMIDE SUBSTITUTED WITH ACETYLTHIO GROUP OR GROUPS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1979-03-13 | — | — | US | disclosed |