Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31651836 | 0.87 | HTR1A (0.61) | LTA4HHTR1ASLC6A2EPHX2SLC6A4 | |
| SCHEMBL11544723 | 0.87 | HTR1A (0.61) | LTA4HHTR1ASLC6A2EPHX2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11549809 | 0.86 | HTR1A (0.60) | LTA4HHTR1ASLC6A2EPHX2SLC6A4 | |
| SCHEMBL11545649 | 0.82 | HTR1A (0.68) | HTR1ASLC6A2EPHX2SLC6A4SLC6A3 | |
| SCHEMBL1026306 | 0.77 | CYP2C19 (0.57) | HTR1ASLC6A2EPHX2HTR3EHTR3B | |
| SCHEMBL11544826 | 0.77 | EPHX2 (0.52) | HTR1ASLC6A2EPHX2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL1969103 | 0.76 | LMNA (0.58) | HTR1ASLC6A2EPHX2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL30069213 | 0.76 | LMNA (0.58) | HTR1ASLC6A2EPHX2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL30069211 | 0.76 | LMNA (0.58) | HTR1ASLC6A2EPHX2HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL26600676 | 0.76 | LMNA (0.58) | HTR1ASLC6A2EPHX2HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |