Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544826 | 0.83 | EPHX2 (0.52) | HTR1ASLC6A2SLC6A4SLC6A3EPHX2 | |
| SCHEMBL11544723 | 0.83 | HTR1A (0.61) | HTR1ASLC6A2SLC6A4SLC6A3EPHX2 | |
| SCHEMBL31651836 | 0.83 | HTR1A (0.61) | HTR1ASLC6A2SLC6A4SLC6A3EPHX2 | |
| SCHEMBL11545602 | 0.82 | LTA4H (0.55) | HTR1ASLC6A2SLC6A4SLC6A3EPHX2 | |
| SCHEMBL234597 | 0.82 | EPHX2 (0.59) | HTR1ASLC6A2EPHX2ADRB1HTR2C | |
| Hydrochloric Acid SCHEMBL11549809 | 0.82 | HTR1A (0.60) | HTR1ASLC6A2SLC6A4SLC6A3EPHX2 | |
| Hydrochloric Acid SCHEMBL1737119 | 0.81 | EPHX2 (0.58) | HTR1ASLC6A2EPHX2ADRB1HTR2C | |
| SCHEMBL1026306 | 0.78 | CYP2C19 (0.57) | HTR1ASLC6A2EPHX2ADRB1 | |
| Hydrochloric Acid SCHEMBL1969103 | 0.77 | LMNA (0.58) | HTR1ASLC6A2EPHX2ADRB1 | |
| Hydrochloric Acid SCHEMBL30069211 | 0.77 | LMNA (0.58) | HTR1ASLC6A2EPHX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |