Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550738 | 0.86 | HTT (0.73) | MAPTHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL9368758 | 0.86 | HTT (0.73) | MAPTHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL24028269 | 0.85 | KMT2A (0.51) | MAPTHTTALDH1A1KMT2ATSHR | |
| SCHEMBL30212752 | 0.85 | KMT2A (0.51) | MAPTHTTALDH1A1KMT2ATSHR | |
| SCHEMBL11545988 | 0.85 | HPGD (0.57) | MAPTHTTALDH1A1KMT2ATSHR | |
| SCHEMBL29034583 | 0.80 | L3MBTL1 (0.75) | MAPTHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL2562988 | 0.80 | SMN1; SMN2 (0.59) | MAPTHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL11551280 | 0.79 | KMT2A (0.67) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL9518079 | 0.78 | AKR1C3 (0.51) | MAPTHTTALDH1A1KMT2ATSHR | |
| SCHEMBL9001650 | 0.78 | MAOA (0.63) | MAPTHTTALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |