Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24028269 | 1.00 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11545748 | 0.85 | MAPT (0.55) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2562988 | 0.83 | SMN1; SMN2 (0.59) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL8752439 | 0.82 | MEN1 (0.66) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11545396 | 0.81 | PARP1 (0.74) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28284716 | 0.81 | MEN1 (0.51) | KMT2AMEN1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL11544934 | 0.80 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL24027984 | 0.80 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29034583 | 0.80 | L3MBTL1 (0.75) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11545988 | 0.80 | HPGD (0.57) | KMT2AMEN1ALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697974-A | Imidazole 3-oxide derivative based ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2023-02-03 | — | — | CN | disclosed |