Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 2/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549982 | 0.84 | HTR2C (0.42) | ALDH1A1HTR2CHTR2BCTSCEPHX2 | |
| SCHEMBL7379917 | 0.83 | KMT2A (0.42) | ELANEHTR2CHTR2BCTSCCYP1A2 | |
| SCHEMBL7373953 | 0.83 | KMT2A (0.42) | ELANEHTR2CHTR2BCTSCCYP1A2 | |
| SCHEMBL11544261 | 0.81 | ELANE (0.38) | ALDH1A1ELANEHTR2CHTR2BCTSC | |
| SCHEMBL11545881 | 0.80 | IDO1 (0.43) | ELANEHTR2CHTR2BCTSCCYP1A2 | |
| SCHEMBL7373153 | 0.79 | KMT2A (0.39) | ELANEHTR2CHTR2BHDAC3HDAC4 | |
| SCHEMBL11547645 | 0.78 | HTR2C (0.42) | ELANEHTR2CHTR2BCTSCCYP1A2 | |
| SCHEMBL11549357 | 0.78 | PRCP (0.39) | HTR2CHTR2BCTSCDPP4 | |
| SCHEMBL10655597 | 0.77 | ELANE (0.43) | ALDH1A1ELANEHTR2CHTR2BCTSC | |
| SCHEMBL11544707 | 0.77 | SLC6A1 (0.41) | ELANEHTR2CHTR2BCTSCCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |