Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428878 | 0.82 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11429507 | 0.81 | HTT (0.50) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11543525 | 0.81 | JAK2 (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL10617304 | 0.80 | CA5A (0.43) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11546286 | 0.80 | GSK3B (0.41) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11547021 | 0.79 | CA5A (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL19908696 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11545759 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11431400 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL11546292 | 0.78 | KMT2A (0.64) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |