Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904829 | 0.82 | TTR (0.62) | TTRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11356523 | 0.82 | MAOB (0.55) | TTRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11356856 | 0.81 | TBK1 (0.50) | TTRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11361243 | 0.81 | TTR (0.42) | TTRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11544426 | 0.80 | NPC1 (0.45) | TTRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL11379997 | 0.76 | TTR (0.44) | TTRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11356857 | 0.75 | TTR (0.56) | TTRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL2907889 | 0.74 | TTR (0.54) | TTRALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11549501 | 0.74 | MEN1 (0.70) | TTRALDH1A1KMT2AMEN1NPC1 | |
| Diethanolamine SCHEMBL11361495 | 0.74 | POLB (0.39) | TTRALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |