Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 9/20 | 0.62 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546372 | 0.82 | TTR (0.64) | TTRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11357037 | 0.81 | GABRP (0.57) | TTRKDM4EALDH1A1GLAMAPT | |
| SCHEMBL11361243 | 0.79 | TTR (0.42) | TTRKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11356856 | 0.79 | TBK1 (0.50) | TTRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11544426 | 0.78 | NPC1 (0.45) | TTRMAOAMAPTNPC1RAB9A | |
| SCHEMBL490420 | 0.77 | TTR (1.00) | TTRMAOAKDM4EALDH1A1GLA | |
| Xanthone SCHEMBL28077164 | 0.76 | TTR (0.75) | TTRMAOAKDM4EALDH1A1GLA | |
| SCHEMBL11360752 | 0.74 | MAOA (0.47) | TTRMAOAKDM4EALDH1A1GLA | |
| SCHEMBL1787556 | 0.74 | TTR (1.00) | TTRMAOAKDM4EALDH1A1GLA | |
| SCHEMBL11356167 | 0.73 | TBK1 (0.52) | TTRMAOAKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | claimed |
| JP-53111096-A | — | — | None | — | — | JP | disclosed |
| JP-54088298-A | — | — | None | — | — | JP | disclosed |
| JP-54115398-A | — | — | None | — | — | JP | disclosed |
| EP-4400110-A1 | OSTEOARTHRITIS PROGRESSION INHIBITOR AND PROGRESSION INHIBITION KIT | Kyushu University, National University Corporation (JP) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023033151-A1 | OSTEOARTHRITIS PROGRESSION INHIBITOR AND PROGRESSION INHIBITION KIT | 国立大学法人九州大学 | 2023-03-09 | — | — | WO | disclosed |
| EP-1968981-B1 | AZAXANTHONES AND USE THEREOF FOR TREATING TUMORS | SUPRATEK PHARMA INC (CA) | 2010-08-18 | — | — | EP | disclosed |
| US-7772255-B2 | Method of treating tumors with azaxanthones | SUPRATEK PHARMA, INC. (CA) | 2010-08-10 | — | — | US | disclosed |
| US-20090042923-A1 | Method of Treating Tumors with Azaxanthones | SEMOV ALEXANDRE | 2009-02-12 | — | — | US | disclosed |
| EP-1968981-A2 | A METHOD OF TREATING TUMORS WITH AZAXANTHONES | Supratek Pharma Inc. (CA) | 2008-09-17 | — | — | EP | disclosed |
| EP-0026675-A1 | 1-Azaxanthone-3-carboxylic acids, their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-04-08 | — | — | EP | disclosed |
| EP-0026675-A1 | 1-Azaxanthone-3-carboxylic acids, their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-04-08 | — | — | EP | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| JP-S54115398-A | 1-AZAXANTHONE-3-CARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1979-09-07 | — | — | JP | disclosed |
| JP-S5488298-A | PRODUCTION OF 1-AZAXANTHONE DERIVATIVE | TAKEDA CHEM IND LTD | 1979-07-13 | — | — | JP | disclosed |
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | disclosed |
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | disclosed |
| JP-S53111096-A | 1-AZAXANTHONE-3-CARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1978-09-28 | — | — | JP | disclosed |
| JP-S05488298-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042923-A1 | Method of Treating Tumors with Azaxanthones | S100A4, S100P, S100B | TTR 1495/4885MAOA 2905/4885KDM4E 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.