Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SOX18 | P35713 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301505 | 0.87 | PLAU (0.47) | PLAUCYP1A2SOX18SLC13A5PDPK1 | |
| SCHEMBL2817046 | 0.84 | TDP1 (0.47) | FFAR1CA1CA2CA9HDAC1 | |
| SCHEMBL8670812 | 0.79 | PLAU (0.59) | PLAUCYP1A2SOX18SLC13A5PDPK1 | |
| Butane SCHEMBL248656 | 0.78 | TDP1 (0.42) | FFAR1CA1CA2CA9 | |
| SCHEMBL16825144 | 0.78 | RAB9A (0.47) | CYP1A2 | |
| SCHEMBL9849307 | 0.75 | CYP19A1 (0.43) | HDAC1 | |
| SCHEMBL7297200 | 0.75 | KMT2A (0.46) | FFAR1 | |
| SCHEMBL17061044 | 0.74 | LMNA (0.53) | FFAR1HDAC1HDAC8 | |
| Biphenyl SCHEMBL11546378 | 0.74 | ESR1 (0.46) | FFAR1HDAC8 | |
| SCHEMBL6240981 | 0.73 | CYP1A2 (0.65) | PLAUCYP1A2SOX18HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35886-E | ENDOTHELIN-CONVERTING ENZYME INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0518299-B1 | Phosphonic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-08 | — | — | EP | disclosed |
| EP-0518299-A2 | Phosphonic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |