Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548596 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2NPSR1TSHR | |
| SCHEMBL2017241 | 0.78 | NPBWR1 (0.37) | ALDH1A1KDM4ESMN1; SMN2MAPK1TSHR | |
| SCHEMBL16797793 | 0.78 | P2RX7 (0.49) | ALDH1A1KDM4ETSHRMAPTMEN1 | |
| SCHEMBL11546359 | 0.77 | KMT2A (0.40) | ALDH1A1KDM4ESMN1; SMN2NPSR1TRIM24 | |
| SCHEMBL11690868 | 0.77 | ALDH1A1 (0.51) | ALDH1A1CYP2A6SMN1; SMN2MAPK1MAPT | |
| SCHEMBL11383777 | 0.76 | ALDH1A1 (0.49) | ALDH1A1CYP2A6KDM4ESMN1; SMN2MAOB | |
| SCHEMBL11550040 | 0.74 | HTT (0.33) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL11378464 | 0.71 | ALDH1A1 (0.40) | ALDH1A1CYP2A6KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL11766757 | 0.71 | HTT (0.47) | ALDH1A1CYP2A6KDM4ESMN1; SMN2MAPT | |
| SCHEMBL11378623 | 0.70 | CYP1A2 (0.41) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138552-A | 4-(V-triazolyl)-styryl optical brighteners | CIBA-GEIGY CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |