Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017241 | 0.84 | NPBWR1 (0.37) | ALDH1A1KMT2ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16797793 | 0.83 | P2RX7 (0.49) | ALDH1A1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL22899915 | 0.81 | NPBWR1 (0.39) | ALDH1A1RAB9AKDM4EHPGDMAPT | |
| SCHEMBL11546993 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL11550040 | 0.80 | HTT (0.33) | ALDH1A1KMT2ARAB9ANPC1GAA | |
| SCHEMBL2019320 | 0.75 | LPL (0.41) | — | |
| SCHEMBL11550625 | 0.73 | NPC1 (0.42) | ALDH1A1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11473126 | 0.72 | NPC1 (0.46) | ALDH1A1KMT2ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26151620 | 0.72 | NPC1 (0.39) | ALDH1A1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24921553 | 0.70 | HTT (0.53) | ALDH1A1KMT2ARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178305-A1 | PYRIDINONE AND PYRIMIDINONE PHOSPHATES AND BORONATES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |
| US-4138552-A | 4-(V-triazolyl)-styryl optical brighteners | CIBA-GEIGY CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |