Triaziquone

Triaziquone

SCHEMBL11547271

CC(CCS)C(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.34
CYP1A2 P05177 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
STAT3 P40763 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GABRR1 P24046 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL6258049 0.89 DNMT1 (0.36) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL21603068 0.85 ACE2 (0.42) DNMT1CYP1A2TP53MAPTSTAT3
Triaziquone SCHEMBL112498 0.83 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL11583629 0.83 DNMT1 (0.41) DNMT1CYP1A2TP53MAPTSTAT3
Triaziquone SCHEMBL6535620 0.82 DNMT1 (0.40) DNMT1CYP1A2TP53MAPTSTAT3
Triaziquone SCHEMBL4082601 0.80 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL983045 0.80 DNMT1 (0.38) DNMT1CYP1A2TP53MAPTSTAT3
Triaziquone SCHEMBL112850 0.79 DNMT1 (0.35) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL6243103 0.78 DNMT1 (0.36) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL11545270 0.78 DNMT1 (0.42) DNMT1CYP1A2TP53MAPTSTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179432-A 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY CINCINNATI MILACRON CHEMICALS, INC. (US) 1979-12-18 US disclosed