Sugi Predict

Sugi Predict / Compounds / SCHEMBL9107343

SCHEMBL9107343

SCHEMBL9107343

COc1cc(N=O)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 2/20 0.57
▸ MEN1 O00255 3/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ GAA P10253 3/20 0.56
▸ RAB9A P51151 2/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ NPC1 O15118 1/20 0.56
▸ HSP90AA1 P07900 1/20 0.56
▸ MAOB P27338 1/20 0.55
▸ SLC22A6 Q4U2R8 1/20 0.53
▸ SLC22A8 Q8TCC7 1/20 0.53
▸ ALDH1A1 P00352 2/20 0.52
▸ TDP1 Q9NUW8 2/20 0.52
▸ TRIM24 O15164 1/20 0.52
▸ HPGD P15428 1/20 0.52
▸ ALDH5A1 P51649 1/20 0.52
▸ ABAT P80404 1/20 0.52
▸ TRIM33 Q9UPN9 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ NPSR1 Q6W5P4 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12844550 0.84 PTGS1 (0.57) PTGS2GAAALDH1A1MAPTPTGS1
SCHEMBL279706 0.81 HTR3E (0.59) PTGS2MEN1KMT2AGAARAB9A
SCHEMBL9499701 0.79 MEN1 (0.58) PTGS2MEN1KMT2AGAARAB9A
SCHEMBL28210948 0.79 PIM1 (0.44) PTGS2MEN1KMT2AGAARAB9A
SCHEMBL12154783 0.78 HTR3E (0.41) PTGS2MEN1KMT2AALDH1A1MAPT
SCHEMBL11547404 0.77 KMT2A (0.39) PTGS2MEN1KMT2AGAARAB9A
SCHEMBL12738623 0.76 AMY1A (0.44) KMT2AGAARAB9AALDH1A1HPGD
SCHEMBL7065017 0.76 ALDH1A1 (0.55) PTGS2MEN1KMT2AGAAL3MBTL1
SCHEMBL13586979 0.76 ALDH1A1 (0.44) MEN1KMT2AGAAL3MBTL1NPC1
SCHEMBL12565706 0.76 MEN1 (0.73) PTGS2MEN1KMT2AGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4425404-A MULTILAYER, PROTECTIVE COATINGS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-01-10 — — US claimed
US-20250263384-A9 REDOX-ACTIVE COMPOUNDS AND USES THEREOF CMBLU ENERGY AG (DE) 2025-08-21 — — US disclosed
US-20240124405-A1 REDOX-ACTIVE COMPOUNDS AND USES THEREOF CMBLU PROJECKT AG (DE) 2024-04-18 — — US disclosed
US-11731945-B2 Redox-active compounds and uses thereof CMBLU ENERGY AG (DE) 2023-08-22 — — US disclosed
US-11731945-B2 Redox-active compounds and uses thereof CMBLU ENERGY AG (DE) 2023-08-22 — — US disclosed
US-11731945-B2 Redox-active compounds and uses thereof CMBLU ENERGY AG (DE) 2023-08-22 — — US disclosed
US-20210253540-A1 REDOX-ACTIVE COMPOUNDS AND USES THEREOF CMBLU PROJEKT AG (DE) 2021-08-19 — — US disclosed
US-20210253540-A1 REDOX-ACTIVE COMPOUNDS AND USES THEREOF CMBLU PROJEKT AG (DE) 2021-08-19 — — US disclosed
CN-113166079-A Redox active compounds and their use 克姆布鲁项目公司 2021-07-23 — — CN disclosed
EP-3837246-A2 REDOX-ACTIVE COMPOUNDS AND USES THEREOF CMBlu Projekt AG (DE) 2021-06-23 — — EP disclosed
WO-2012074536-A1 PROCESS FOR THE PREPARATION OF 2-METHOXYMETHYL-1,4-BENZENEDIAMINE, ITS DERIVATIVES THEREOF AND THE SALTS THEREOF THE PROCTER & GAMBLE COMPANY (US) 2012-06-07 — — WO disclosed
US-20120142969-A1 Process for the Preparation of 2-Methoxymethyl-1,4-Benzenediamine, Its Derivatives Thereof and the Salts Thereof WELLA OPERATIONS US, LLC 2012-06-07 — — US disclosed
US-7851501-B2 Aromatic nitrocatechol compounds and their use for modulating processes mediated by cell adhesion molecules REVOTAR BIOPHARMACEUTICALS AG (DE) 2010-12-14 — — US disclosed
US-20090105280-A1 Novel Aromatic Nitro Compounds REVOTAR BIOPHARMACEUTICALS AG (DE) 2009-04-23 — — US disclosed
US-7514556-B2 Inhibitors of β-lactamase METHYLGENE INC. (CA) 2009-04-07 — — US disclosed
EP-0229014-B1 MAGNETIC RECORDING MEDIUM SONY CORPORATION (JP) 1993-03-24 — — EP disclosed
US-4735848-A PERFLUOROALKYL ESTER LUBRICANT SONY CORPORATION (JP) 1988-04-05 — — US disclosed
EP-0229014-A2 Magnetic recording medium SONY CORPORATION (JP) 1987-07-15 — — EP disclosed
US-4425404-A MULTILAYER, PROTECTIVE COATINGS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-01-10 — — US disclosed
EP-0093194-A2 Magnetic recording medium MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1983-11-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124405-A1 REDOX-ACTIVE COMPOUNDS AND USES THEREOF NOX4, NQO1, GPX1 PTGS2 1546/4885MEN1 4552/4885KMT2A 1859/4885
US-20120142969-A1 Process for the Preparation of 2-Methoxymethyl-1,4-Benzenediamine, Its Derivatives Thereof and the Salts Thereof KRT18, VIM, KDM4B PTGS2 2488/4885MEN1 2670/4885KMT2A 157/4885
US-20090105280-A1 Novel Aromatic Nitro Compounds SELP, SELE, SELL PTGS2 734/4885MEN1 4614/4885KMT2A 3098/4885
US-20250263384-A9 REDOX-ACTIVE COMPOUNDS AND USES THEREOF NOX4, NQO1, GPX1 PTGS2 1546/4885MEN1 4552/4885KMT2A 1859/4885
US-11731945-B2 Redox-active compounds and uses thereof NOX4, NQO1, GPX1 PTGS2 1546/4885MEN1 4552/4885KMT2A 1859/4885
US-20210253540-A1 REDOX-ACTIVE COMPOUNDS AND USES THEREOF NOX4, NQO1, GPX1 PTGS2 1546/4885MEN1 4552/4885KMT2A 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.