SCHEMBL11547445

SCHEMBL11547445

CC1CC(C)C(c2ccccc2)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 3/20 0.44
SIGMAR1 Q99720 3/20 0.39
MAOA P21397 6/20 0.35
MAOB P27338 6/20 0.35
KDM1A O60341 4/20 0.35
CYP2C19 P33261 4/20 0.35
CYP2B6 P20813 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
HTR2C P28335 2/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2A6 P11509 1/20 0.35
SLC6A2 P23975 1/20 0.35
ADRA1A P35348 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036589 0.77 SIGMAR1 (0.47) SIGMAR1HTR2CHTR2AHTR2BHRH3
SCHEMBL7599981 0.77 SIGMAR1 (0.47) SIGMAR1HTR2CHTR2AHTR2BHRH3
SCHEMBL7609590 0.77 SIGMAR1 (0.47) SIGMAR1HTR2CHTR2AHTR2BHRH3
SCHEMBL7609588 0.77 SIGMAR1 (0.47) SIGMAR1HTR2CHTR2AHTR2BHRH3
SCHEMBL7599978 0.77 SIGMAR1 (0.47) SIGMAR1HTR2CHTR2AHTR2BHRH3
SCHEMBL30298332 0.77 ALDH1A1 (0.43) KDM1AHTR2CHTR2AHTR2B
SCHEMBL413656 0.77 ALDH1A1 (0.43) KDM1AHTR2CHTR2AHTR2B
SCHEMBL1389049 0.75 EDNRA (0.52) EDNRASIGMAR1EDNRB
Bromide SCHEMBL28348255 0.74 ALDH1A1 (0.42) KDM1AHTR2CHTR2AHTR2B
SCHEMBL7912606 0.73 SIGMAR1 (0.49) SIGMAR1HTR2CHTR2AHTR2BHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4151182-A CATALYTIC OXIDATION FROM INDANS OR DIPHENYLMETHANE DERIVATIVES BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed