Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5110887 | 0.85 | NPC1 (0.63) | ACHEKMT2AGLAHDAC3HDAC4 | |
| SCHEMBL2324962 | 0.85 | FAAH (0.49) | ACHENPC1RAB9A | |
| SCHEMBL4769744 | 0.84 | KMT2A (0.57) | ACHEKMT2AGLAHDAC3HDAC4 | |
| SCHEMBL21382248 | 0.84 | KMT2A (0.57) | ACHEKMT2AGLAHDAC3HDAC4 | |
| SCHEMBL8585756 | 0.83 | KMT2A (0.56) | ACHEKMT2AGLAHDAC3HDAC4 | |
| SCHEMBL11547458 | 0.83 | ACHE (0.48) | ACHEKMT2AGLA | |
| SCHEMBL28219082 | 0.82 | MGLL (0.60) | ACHEKMT2AGLAMEN1NPC1 | |
| SCHEMBL27887140 | 0.82 | KMT2A (0.55) | ACHEKMT2AGLAHDAC3HDAC4 | |
| SCHEMBL28364907 | 0.81 | CA1 (0.54) | ACHEKMT2AGLAHDAC3HDAC4 | |
| SCHEMBL30661069 | 0.81 | KMT2A (0.53) | ACHEKMT2AGLAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500865-B1 | POTENTIATING GLUTAMATE RECEPTORS BY ADMINISTERING N-1-(4-(4-(2-METHANESULFONAMIDO ETHYL)PHENY)PHENYL)ETHYL 2-PROPANE SULFONAMIDE FOR LEARNING ENHANCEMENT AND PROPHYLAXIS OF NEURODEGENERATIVE DISORDERS, PSYCHOSIS OR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY | 2002-12-31 | — | — | US | disclosed |