SCHEMBL11547707

SCHEMBL11547707

CCOC(C)(C)CCCC(C)CCOc1c(CC)cccc1CC

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PTGES O14684 1/20 0.35
PPARG P37231 1/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.32
MAPK1 P28482 2/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11550411 0.93 SCN2A (0.34) ALOX5PTGESPPARGL3MBTL1MAPK1
SCHEMBL11549300 0.86 L3MBTL1 (0.48) ALOX5PTGESPPARGL3MBTL1TDP1
SCHEMBL11550011 0.86 SCN2A (0.39) TSHR
SCHEMBL11546435 0.85 ALOX15 (0.37) GABRA1TSHR
SCHEMBL11548975 0.79 SMN1; SMN2 (0.43) ALOX5PTGESPPARGL3MBTL1MAPK1
SCHEMBL11551517 0.79 PPARG (0.37) ALOX5PTGESPPARGL3MBTL1MAPK1
SCHEMBL11547255 0.79 MAPK1 (0.53) L3MBTL1MAPK1TSHRTDP1
SCHEMBL11547888 0.79 POLB (0.41) L3MBTL1MAPK1TDP1MAPT
SCHEMBL11553217 0.78 LMNA (0.40) ALOX5PPARGMAPT
SCHEMBL11545511 0.76 MAPT (0.35) ALOX5PTGESPPARGL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4137273-A INSECTICIDES, CHEMICAL INTERMEDIATES ZOECON CORPORATION (US) 1979-01-30 US disclosed