Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547707 | 0.79 | ALOX5 (0.35) | PTGESALOX5PPARGMAPK1L3MBTL1 | |
| SCHEMBL11547530 | 0.77 | KDM4E (0.52) | SMN1; SMN2ALDH1A1KDM4ELMNAMAPK1 | |
| SCHEMBL11549300 | 0.76 | L3MBTL1 (0.48) | KDM4EHPGDHTTPTGESALOX5 | |
| SCHEMBL11550011 | 0.76 | SCN2A (0.39) | ALDH1A1KDM4ELMNASLC6A4HTR2B | |
| SCHEMBL11550411 | 0.76 | SCN2A (0.34) | ALDH1A1KDM4EPTGESALOX5PPARG | |
| SCHEMBL11549696 | 0.76 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1ALOX5L3MBTL1PPARA | |
| SCHEMBL11546435 | 0.75 | ALOX15 (0.37) | — | |
| SCHEMBL11545511 | 0.74 | MAPT (0.35) | ALDH1A1HPGDHTTPTGESALOX5 | |
| SCHEMBL27981723 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4ENPC1HSP90AA1 | |
| SCHEMBL11546482 | 0.73 | TDP1 (0.34) | ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137273-A | INSECTICIDES, CHEMICAL INTERMEDIATES | ZOECON CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |