SCHEMBL11547744

SCHEMBL11547744

O=C1OC(=O)c2cc3c(Br)ccc(Br)c3cc21

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 1/20 0.39
TYMS P04818 3/20 0.38
HSP90AA1 P07900 1/20 0.34
TLR9 Q9NR96 1/20 0.34
S100A4 P26447 1/20 0.34
PTPRC P08575 1/20 0.34
HTT P42858 1/20 0.34
CYP1B1 Q16678 1/20 0.33
TSHR P16473 1/20 0.33
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25233080 0.81 MEN1 (0.48) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL855808 0.79 ALOX15 (0.48) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL11549347 0.78 TSHR (0.46) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL27403656 0.75 ALOX15 (0.43) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL1356074 0.74 TYMS (0.43) ALOX15TDP1ALDH1A1TYMSS100A4
SCHEMBL29362967 0.74 TYMS (0.61) ALDH1A1TYMSCYP1B1
SCHEMBL320954 0.74 TYMS (0.61) ALDH1A1TYMSCYP1B1
SCHEMBL3993249 0.73 TDP1 (0.59) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL135902 0.71 S100A4 (0.56) ALOX15TDP1ALDH1A1S100A4PTPRC
SCHEMBL26882702 0.71 ALOX15 (0.46) ALOX15TDP1ALDH1A1TYMSHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4167506-A Diazaphenalene derivatives and resin containing color compositions TEIJIN LIMITED (JP) 1979-09-11 US disclosed