SCHEMBL11549347

SCHEMBL11549347

O=C1OC(=O)c2cc3c(Br)c(Br)c(Br)c(Br)c3cc21

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ALOX15 P16050 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.36
TYMS P04818 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11547744 0.78 ALOX15 (0.46) TSHRALOX15TDP1ALDH1A1TYMS
SCHEMBL855808 0.76 ALOX15 (0.48) TSHRALOX15TDP1ALDH1A1TYMS
SCHEMBL3993249 0.74 TDP1 (0.59) TSHRALOX15TDP1ALDH1A1TYMS
SCHEMBL27403656 0.72 ALOX15 (0.43) TSHRALOX15TDP1ALDH1A1TYMS
SCHEMBL25233080 0.70 MEN1 (0.48) TSHRALOX15TDP1ALDH1A1TYMS
SCHEMBL26882702 0.68 ALOX15 (0.46) ALOX15TDP1ALDH1A1TYMS
SCHEMBL135902 0.68 S100A4 (0.56) ALOX15TDP1ALDH1A1
SCHEMBL734024 0.67 ALOX15 (0.39) TSHRALOX15TDP1ALDH1A1TYMS
SCHEMBL854455 0.67 ALOX15 (0.39) TSHRALOX15TDP1ALDH1A1TYMS
SCHEMBL195704 0.65 TSHR (0.52) TSHRALOX15TDP1ALDH1A1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4167506-A Diazaphenalene derivatives and resin containing color compositions TEIJIN LIMITED (JP) 1979-09-11 US disclosed