Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 11/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549141 | 0.83 | ATM (0.53) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11547838 | 0.82 | ADRB1 (0.56) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11549418 | 0.82 | ADRB2 (0.48) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11547627 | 0.81 | ABCB1 (0.43) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11551271 | 0.81 | ADRB1 (0.49) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11546061 | 0.81 | ATM (0.53) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11547110 | 0.80 | ADRB2 (0.51) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11884013 | 0.79 | ADRB1 (0.49) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11652457 | 0.79 | ADRB1 (0.49) | ADRB1ADRB3ADRB2CYP1A2ATM | |
| SCHEMBL11545209 | 0.77 | ATM (0.53) | ADRB1ADRB3ADRB2CYP1A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |