Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546259 | 0.80 | RAB9A (0.50) | ACE | |
| SCHEMBL11544257 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL7380820 | 0.78 | ACE (0.54) | ACE | |
| Water SCHEMBL5570208 | 0.77 | ACE (0.52) | ACE | |
| SCHEMBL11359125 | 0.76 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL9501764 | 0.76 | ACE (0.55) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL9500411 | 0.75 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL11546843 | 0.75 | ACE (0.51) | ACE | |
| SCHEMBL5742878 | 0.74 | CACNA1A (0.62) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL5742876 | 0.74 | CACNA1A (0.62) | ALDH1A1SMN1; SMN2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |