Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723290 | 0.75 | LMNA (0.45) | MERTKVCAM1LMNANPC1RAB9A | |
| SCHEMBL2972082 | 0.73 | SLC9A1 (0.60) | LMNANPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL14606513 | 0.71 | MERTK (0.40) | MERTKVCAM1LMNANPSR1ALDH1A1 | |
| SCHEMBL2403679 | 0.70 | VCAM1 (0.51) | MERTKVCAM1PKMNPSR1ALDH1A1 | |
| SCHEMBL31592017 | 0.70 | TSHR (0.52) | VCAM1PKMNPSR1GPR35ALDH1A1 | |
| SCHEMBL3633645 | 0.70 | TSHR (0.52) | VCAM1PKMNPSR1GPR35ALDH1A1 | |
| SCHEMBL10658746 | 0.70 | VCAM1 (0.44) | VCAM1LMNAPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL15927426 | 0.70 | ALDH1A1 (0.49) | MERTKVCAM1PKMNPSR1ALDH1A1 | |
| SCHEMBL1455497 | 0.69 | POLB (0.60) | LMNANPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL864500 | 0.69 | TSHR (0.50) | VCAM1ALDH1A1RECQLCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151298-A | ANILINOMETHYLENEMALONONITRILE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |