Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140146 | 0.88 | PTGS1 (0.52) | PPARGPPARAPTGS1PTGS2LMNA | |
| Methoxymethane SCHEMBL11481514 | 0.87 | PPARG (0.49) | PPARGPPARAPTGS1PTGS2LMNA | |
| SCHEMBL8128147 | 0.84 | PTGS1 (0.45) | PTGS1PTGS2LMNACXCR1CXCR2 | |
| SCHEMBL9544312 | 0.81 | THRA (0.46) | PTGS1PTGS2LMNACXCR1CXCR2 | |
| Ether SCHEMBL28789517 | 0.77 | LOXL2 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30089557 | 0.76 | PTGS1 (0.53) | PTGS1PTGS2LMNACXCR1CXCR2 | |
| SCHEMBL7716957 | 0.75 | MAPT (0.47) | PPARGPPARACYP2C9SMN1; SMN2KMT2A | |
| SCHEMBL8083048 | 0.75 | HSD17B3 (0.58) | PTGS1PTGS2LMNACXCR1CXCR2 | |
| SCHEMBL28403117 | 0.74 | PTGS1 (0.52) | PTGS1PTGS2LMNACXCR1CXCR2 | |
| SCHEMBL9441164 | 0.74 | PTGS1 (0.52) | PTGS1PTGS2LMNACXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142054-A | TRIVALENT THALLIUM SALT | THE UPJOHN COMPANY (US) | 1979-02-27 | — | — | US | disclosed |