SCHEMBL11549002

SCHEMBL11549002

CCOC1Oc2ccccc2O1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.37
ALDH1A1 P00352 4/20 0.35
TSHR P16473 2/20 0.34
POLB P06746 1/20 0.34
ESR2 Q92731 1/20 0.34
NPC1 O15118 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23558872 0.79 THRB (0.37) ALDH1A1POLBTHRBMAPK1L3MBTL1
SCHEMBL7554881 0.78 TSHR (0.43) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL23558878 0.78 POLB (0.36) CA2ALDH1A1TSHRPOLBUSP2
SCHEMBL3625885 0.77 CA2 (0.37) CA2
SCHEMBL31633770 0.77 HTR2C (0.33) ALDH1A1POLBKDM4EUSP2GAA
SCHEMBL23558909 0.77 ESR1 (0.38) CA2ESR2
Pyrogallol SCHEMBL8720185 0.74 ALDH1A1 (0.36) CA2ALDH1A1NPC1KDM4EHSD17B10
SCHEMBL11908262 0.74 CA2 (0.33) CA2
SCHEMBL6619829 0.73 CA2 (0.36) CA2ALDH1A1NPC1L3MBTL1
SCHEMBL16234757 0.73 ALDH1A1 (0.42) ALDH1A1TSHRHSD17B10NPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4155915-A POSTEMERGENCE AND PREEMERGENCE HERBICIDES SCHERING AKTIENGESELLSCHAFT (DE) 1979-05-22 US disclosed