Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989929 | 0.84 | — | — | |
| SCHEMBL4018942 | 0.82 | PDXK (0.37) | HDAC8PDXK | |
| SCHEMBL10535166 | 0.71 | TDP1 (0.48) | GRM5TP53TDP1PTGS2 | |
| SCHEMBL4022995 | 0.71 | HDAC8 (0.39) | GRM5HDAC8PTGS2 | |
| SCHEMBL1638461 | 0.69 | PDXK (0.43) | HDAC8TP53TDP1PTGS2PDXK | |
| SCHEMBL6551393 | 0.69 | HDAC8 (0.46) | GRM5HDAC8TP53TDP1PTGS2 | |
| SCHEMBL28342562 | 0.68 | PDXK (0.42) | TP53TDP1PTGS2PDXK | |
| SCHEMBL30471364 | 0.68 | — | — | |
| SCHEMBL1521255 | 0.68 | — | — | |
| SCHEMBL25401092 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154772-A | PHENOLIC RESIN CONNECTED TO ADDITION POLYMER | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154773-A | UREA-ALDEHYDE POLYMER COUPLED TO ADDITION POLYMER | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-05-15 | — | — | US | disclosed |