Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549658 | 0.85 | MAPT (0.42) | HTTNPC1PKMRAB9ANPSR1 | |
| SCHEMBL11555249 | 0.81 | CNR1 (0.50) | HTTASIC3MAPTALDH1A1PDK2 | |
| SCHEMBL11551461 | 0.81 | ALDH1A1 (0.46) | HTTNPC1RAB9AASIC3MAPT | |
| SCHEMBL11551871 | 0.79 | NPSR1 (0.43) | NPC1PKMRAB9ANPSR1MAPT | |
| SCHEMBL30807950 | 0.79 | HTT (0.44) | HTTNPC1PKMRAB9AASIC3 | |
| SCHEMBL11550210 | 0.78 | TNIK (0.45) | HTTASIC3MAPTL3MBTL1LMNA | |
| SCHEMBL19604555 | 0.78 | CYP1A1 (0.59) | NPC1PKMRAB9ANPSR1MAPT | |
| SCHEMBL23335287 | 0.77 | HTT (0.39) | HTTMAPTALDH1A1PTGES2 | |
| SCHEMBL12391039 | 0.76 | ASIC3 (0.50) | HTTNPC1RAB9AASIC3MAPT | |
| SCHEMBL23335299 | 0.76 | ALDH2 (0.37) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |