Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700507 | 0.94 | HTT (0.46) | TNIKHTTASIC3LMNAL3MBTL1 | |
| SCHEMBL17616893 | 0.84 | ASIC3 (0.43) | TNIKHTTASIC3LMNAL3MBTL1 | |
| SCHEMBL11552961 | 0.84 | HAO1 (0.49) | TNIKHTTASIC3LMNAL3MBTL1 | |
| SCHEMBL12391039 | 0.83 | ASIC3 (0.50) | HTTASIC3LMNAL3MBTL1MAPT | |
| SCHEMBL11548872 | 0.83 | ESR2 (0.50) | TNIKHTTASIC3CYP17A1CYP1A1 | |
| SCHEMBL12711693 | 0.82 | MMP3 (0.47) | HTTASIC3LMNAL3MBTL1MAPT | |
| SCHEMBL11549319 | 0.82 | MAPT (0.41) | TNIKHTTMAPTCYP17A1FFAR1 | |
| SCHEMBL11554460 | 0.81 | MAPT (0.51) | TNIKHTTASIC3LMNAL3MBTL1 | |
| SCHEMBL11216394 | 0.81 | ASIC3 (0.41) | HTTASIC3LMNAL3MBTL1MAPT | |
| SCHEMBL29096081 | 0.78 | HSD11B1 (0.37) | TNIKHTTASIC3LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | claimed |
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |