Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549900 | 1.00 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1KMT2ALMNACHRM2 | |
| SCHEMBL11549897 | 1.00 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1KMT2ALMNACHRM2 | |
| SCHEMBL11550062 | 0.88 | ACHE (0.41) | SIGMAR1CHRM2HTR1ACHRM1 | |
| SCHEMBL11550057 | 0.88 | ACHE (0.41) | SIGMAR1CHRM2HTR1ACHRM1 | |
| SCHEMBL11550069 | 0.88 | ACHE (0.41) | SIGMAR1CHRM2HTR1ACHRM1 | |
| SCHEMBL11543930 | 0.79 | HRH3 (0.42) | SIGMAR1CHRM2HTR1ACYP2D6CHRM1 | |
| SCHEMBL11623448 | 0.78 | SIGMAR1 (0.51) | SIGMAR1LMNAHTR1AMETAP1 | |
| Hydrochloric Acid SCHEMBL11623696 | 0.77 | HTR1A (0.51) | SIGMAR1LMNAHTR1AMETAP1 | |
| SCHEMBL11549243 | 0.75 | CYP1A2 (0.33) | SIGMAR1ALDH1A1KMT2ALMNACHRM2 | |
| SCHEMBL11549261 | 0.75 | CYP1A2 (0.33) | SIGMAR1ALDH1A1KMT2ALMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156723-A | HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1979-05-29 | — | — | US | disclosed |