Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679299 | 0.81 | L3MBTL1 (0.50) | THRATHRBPIK3CAKMT2AMAPT | |
| SCHEMBL11551105 | 0.72 | KDM4E (0.59) | KMT2AMAPTALDH1A1L3MBTL1NPC1 | |
| SCHEMBL11551446 | 0.71 | TTR (0.42) | MAPTALDH1A1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27988478 | 0.71 | ACHE (0.44) | THRBKMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL11551512 | 0.70 | KDM4E (0.54) | KMT2AMAPTALDH1A1L3MBTL1NPC1 | |
| SCHEMBL11807876 | 0.70 | NPC1 (0.44) | THRATHRBKMT2AMAPTALDH1A1 | |
| SCHEMBL11838170 | 0.70 | NPC1 (0.46) | KMT2AMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11552376 | 0.70 | TTR (0.43) | ALDH1A1NPC1RAB9ALMNASTS | |
| SCHEMBL11553175 | 0.69 | KDM4E (0.39) | KMT2AALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL11554538 | 0.69 | HRH3 (0.65) | KMT2AALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146624-A | METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |