Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546721 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11550473 | 0.89 | MITF (0.46) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11331252 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11454717 | 0.87 | KMT2A (0.43) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11465272 | 0.87 | KMT2A (0.43) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11336631 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11341207 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11332173 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11549687 | 0.86 | OPRM1 (0.49) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL11573548 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156014-A | N-(2-aminocycloheptyl)alkanoylanilides and in the treatment of depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | claimed |
| US-4159339-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4156014-A | N-(2-aminocycloheptyl)alkanoylanilides and in the treatment of depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |