Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620900 | 0.94 | ASIC3 (0.44) | ASIC3L3MBTL1LMNAMAPTHTT | |
| Bicarbonate SCHEMBL28546564 | 0.87 | HAO1 (0.45) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL17616893 | 0.84 | ASIC3 (0.43) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL11551623 | 0.84 | HAO1 (0.49) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL12391039 | 0.83 | ASIC3 (0.50) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL11549060 | 0.83 | ASIC3 (0.42) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL12711693 | 0.82 | MMP3 (0.47) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL11551589 | 0.82 | MAPT (0.41) | MAPTALDH1A1MAPK1LSSCYP1A1 | |
| SCHEMBL11554460 | 0.81 | MAPT (0.51) | ASIC3L3MBTL1LMNAMAPTHTT | |
| SCHEMBL11550210 | 0.81 | TNIK (0.45) | ASIC3L3MBTL1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322432-A | Cyclopropanecarboxylic acid alkynyl esters, processes for producing them, and their use as pesticides | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |