Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CTSE | P14091 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550220 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3ALDH1A1SIGMAR1 | |
| SCHEMBL11550690 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3ALDH1A1SIGMAR1 | |
| SCHEMBL11252676 | 0.84 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3ALDH1A1SIGMAR1 | |
| SCHEMBL11539811 | 0.81 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3SIGMAR1CTSD | |
| SCHEMBL11183841 | 0.81 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3SIGMAR1CTSD | |
| SCHEMBL11183844 | 0.81 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3SIGMAR1CTSD | |
| SCHEMBL11076649 | 0.80 | SIGMAR1 (0.49) | SLC6A4SLC6A2SLC6A3ALDH1A1SIGMAR1 | |
| SCHEMBL11079211 | 0.80 | SIGMAR1 (0.49) | SLC6A4SLC6A2SLC6A3ALDH1A1SIGMAR1 | |
| SCHEMBL11076652 | 0.80 | SIGMAR1 (0.49) | SLC6A4SLC6A2SLC6A3ALDH1A1SIGMAR1 | |
| SCHEMBL11076589 | 0.77 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141893-A | Decahydrocyclopent[c]azepines | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | disclosed |