Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550991 | 0.82 | TACR1 (0.52) | POLBALDH1A1 | |
| SCHEMBL11827418 | 0.81 | ALDH1A1 (0.54) | POLBALDH1A1KDM4EDRD2DRD4 | |
| SCHEMBL7247628 | 0.79 | SIGMAR1 (0.68) | POLBSIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7246143 | 0.78 | SIGMAR1 (0.67) | POLBSIGMAR1MEN1KMT2A | |
| SCHEMBL11552756 | 0.78 | DRD2 (0.48) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL7798941 | 0.77 | TACR1 (0.48) | HTR1DHTR1BDRD2DRD4DRD3 | |
| SCHEMBL11825414 | 0.76 | DRD2 (0.61) | POLBALDH1A1KDM4EDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7800871 | 0.76 | TACR1 (0.47) | HTR1DHTR1BDRD2DRD4DRD3 | |
| SCHEMBL16256958 | 0.75 | OPRM1 (0.55) | SIGMAR1 | |
| SCHEMBL615742 | 0.74 | AVPR1A (0.61) | POLBALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148796-A | γ-Piperidinobutyrophenones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-04-10 | — | — | US | disclosed |