Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551109 | 0.78 | SIGMAR1 (0.56) | HRH3SIGMAR1HRH1CYP1A2CYP2D6 | |
| SCHEMBL11675971 | 0.77 | HRH3 (0.41) | HRH3SIGMAR1HRH1GRIN2DGRIN3B | |
| SCHEMBL11550530 | 0.76 | SIGMAR1 (0.45) | MEN1KMT2AATMSIGMAR1TP53 | |
| SCHEMBL11552120 | 0.76 | CYP1A2 (0.42) | RAB9ASIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL11554624 | 0.75 | CYP1A2 (0.43) | MEN1KMT2AATMRAB9ASIGMAR1 | |
| SCHEMBL11554941 | 0.74 | SIGMAR1 (0.47) | HRH3MEN1KMT2AATMSIGMAR1 | |
| SCHEMBL11751266 | 0.71 | MAOB (0.60) | HRH3SIGMAR1HRH1 | |
| SCHEMBL31604928 | 0.68 | SLC26A4 (0.47) | HRH3MEN1KMT2AATMABCB1 | |
| SCHEMBL11550232 | 0.65 | CYP1A2 (0.50) | MEN1KMT2ARAB9AGRIN2DCYP1A2 | |
| SCHEMBL1797372 | 0.65 | SIGMAR1 (0.66) | HRH3SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146624-A | METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |