Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677856 | 0.80 | HTT (0.39) | HRH3SIGMAR1CYP1A2TP53CYP2D6 | |
| SCHEMBL11782472 | 0.79 | HRH1 (0.58) | HRH3SIGMAR1GRIN2BKDM4EL3MBTL1 | |
| SCHEMBL11550534 | 0.77 | HRH3 (0.41) | HRH3SIGMAR1CYP1A2TP53CYP2D6 | |
| SCHEMBL11680152 | 0.77 | SIGMAR1 (0.58) | HRH3SIGMAR1GRIN2BKDM4EL3MBTL1 | |
| SCHEMBL11679521 | 0.77 | TMEM97 (0.36) | SIGMAR1CYP1A2TP53CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL11678798 | 0.76 | SIGMAR1 (0.56) | HRH3SIGMAR1GRIN2BKDM4EL3MBTL1 | |
| SCHEMBL11675968 | 0.74 | L3MBTL1 (0.58) | TP53TSHRHTTKDM4EL3MBTL1 | |
| SCHEMBL11679983 | 0.74 | TMEM97 (0.38) | SIGMAR1TP53TSHRHTTKDM4E | |
| SCHEMBL11780778 | 0.73 | HRH3 (0.61) | HRH3TP53CYP2D6TSHRHTT | |
| SCHEMBL11779218 | 0.67 | KDM4E (0.49) | HRH3SIGMAR1CYP1A2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |