Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554941 | 0.86 | SIGMAR1 (0.47) | SIGMAR1MCHR1ALDH1A1MAPTHPGD | |
| SCHEMBL11675968 | 0.81 | L3MBTL1 (0.58) | MCHR1ALDH1A1MAPTHPGDTHRB | |
| SCHEMBL11551512 | 0.78 | KDM4E (0.54) | MCHR1ALDH1A1MAPTHPGDMAOB | |
| SCHEMBL11552117 | 0.78 | TTR (0.38) | MCHR1ALDH1A1HPGDTP53HSD17B10 | |
| SCHEMBL11551316 | 0.77 | ALPL (0.61) | SIGMAR1MCHR1ALDH1A1MAPTHPGD | |
| SCHEMBL11551105 | 0.77 | KDM4E (0.59) | MCHR1ALDH1A1MAPTHPGDMAOB | |
| SCHEMBL11552125 | 0.77 | ALDH1A1 (0.52) | MCHR1ALDH1A1MAPTHPGDMAOB | |
| Hydrochloric Acid SCHEMBL29794111 | 0.76 | ALPL (0.64) | SIGMAR1MCHR1ALDH1A1MAPTHPGD | |
| SCHEMBL11550534 | 0.76 | HRH3 (0.41) | SIGMAR1TP53KMT2ATSHRMEN1 | |
| SCHEMBL6841232 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDMAOBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146624-A | METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |