Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559725 | 0.95 | TP53 (0.44) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11552075 | 0.93 | GUSB (0.47) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11375670 | 0.91 | GUSB (0.56) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11390124 | 0.88 | PDE5A (0.41) | TP53POLBMAPTTDP1KDM4E | |
| SCHEMBL11556064 | 0.86 | GUSB (0.49) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11554058 | 0.86 | GUSB (0.51) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11375677 | 0.85 | PDE5A (0.54) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11549969 | 0.84 | GUSB (0.49) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11374443 | 0.84 | GUSB (0.53) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11384755 | 0.83 | PDE5A (0.42) | GUSBTP53POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |